BDBM50124352 CHEMBL3623441

SMILES CC(C)C(=O)Nc1ncc(s1)-c1ccncc1-c1ccccc1Cl

InChI Key InChIKey=ROPKDJGJHNEEFN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50124352   

TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50124352(CHEMBL3623441)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant N-terminal 6His-tagged LIMK1 (unknown origin) expressed in Sf21 cells by HTRF assay using cofilin as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50124352(CHEMBL3623441)
Affinity DataIC50:  800nMAssay Description:Inhibition of LIMK1 in human ZR75-1 cells assessed as inhibition of cofilin phosphorylation after 5 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed