BDBM50124482 5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-[2-(5-thioxo-2,5-dihydro-[1,2,4]oxadiazol-3-yl)-pyridin-4-yl]-pyrimidin-4-yl}-amide::CHEMBL176999

SMILES C#CCOc1nc(-c2ccnc(-c3nc(=S)o[nH]3)c2)nc(NS(=O)(=O)c2ccc(C(C)C)cn2)c1Oc1ccccc1OC

InChI Key InChIKey=HTNBCWLAXCOARB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50124482   

TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50124482BDBM50124482(5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy...)
Affinity DataIC50: 27nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50124482BDBM50124482(5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy...)
Affinity DataIC50: 366nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed