BDBM50124487 5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-[2-(1H-tetrazol-5-yl)-pyridin-4-yl]-pyrimidin-4-yl}-amide::CHEMBL176664

SMILES C#CCOc1nc(-c2ccnc(-c3nnn[nH]3)c2)nc(NS(=O)(=O)c2ccc(C)cn2)c1Oc1ccccc1OC

InChI Key InChIKey=NZOSZZWWOMARMH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50124487   

TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50124487BDBM50124487(5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-ph...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50124487BDBM50124487(5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-ph...)
Affinity DataIC50: 1.03E+3nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed