BDBM50124921 CHEMBL159558::N-(3-Chloro-benzyl)-4-trifluoromethyl-benzamidine

SMILES NC(=NCc1cccc(Cl)c1)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=RNEJFUFEMICGEG-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50124921   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124921(N-(3-Chloro-benzyl)-4-trifluoromethyl-benzamidine ...)
Affinity DataKi:  20nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124921(N-(3-Chloro-benzyl)-4-trifluoromethyl-benzamidine ...)
Affinity DataIC50: 32nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed