BDBM50125107 6-{4-[(Biphenyl-2-carbonyl)-amino]-3-chloro-benzoyl}-3,4,5,6-tetrahydro-1H-azepino[4,3,2-cd]indole-2-sulfonic acid::CHEMBL166135

SMILES O=C(Nc1ccc(C(=O)N2CCCc3c(S(=O)(=O)O)[nH]c4cccc2c34)cc1Cl)c1ccccc1-c1ccccc1

InChI Key InChIKey=BSYJKVFQOQUJQQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125107   

TargetVasopressin V2 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50125107BDBM50125107(6-{4-[(Biphenyl-2-carbonyl)-amino]-3-chloro-benzoy...)
Affinity DataIC50: 12nMAssay Description:Inhibitory activity of the human V2 receptor was assessed by the accumulation of cAMP in transfected HEK293 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed