BDBM50125173 1-(2-Amino-4-fluoro-phenyl)-4-(7bS,11aR)-6,7,8,9,11,11a-hexahydro-5H,7bH-4-thia-7a,10-diaza-cyclohepta[jk]fluoren-10-yl-butan-1-one::CHEMBL166310

SMILES Nc1cc(F)ccc1C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3SCCCN2c13

InChI Key InChIKey=DPASSLWFBPICMV-FPOVZHCZSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50125173   

Target5-hydroxytryptamine receptor 2A(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125173(1-(2-Amino-4-fluoro-phenyl)-4-(7bS,11aR)-6,7,8,9,1...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor using [125I]-DOI as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2A(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125173(1-(2-Amino-4-fluoro-phenyl)-4-(7bS,11aR)-6,7,8,9,1...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity towards DA D2 receptor using [3H]-N-methyl-spiperone as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125173(1-(2-Amino-4-fluoro-phenyl)-4-(7bS,11aR)-6,7,8,9,1...)
Affinity DataKi:  2.70nMAssay Description:Binding affinity towards DA D2 receptor using [3H]-N-methyl-spiperone as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125173(1-(2-Amino-4-fluoro-phenyl)-4-(7bS,11aR)-6,7,8,9,1...)
Affinity DataKi:  4.10nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor using [125I]-DOI as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125173(1-(2-Amino-4-fluoro-phenyl)-4-(7bS,11aR)-6,7,8,9,1...)
Affinity DataKi:  82nMAssay Description:Binding affinity towards DA D2 receptor using [3H]-N-methyl-spiperone as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125173(1-(2-Amino-4-fluoro-phenyl)-4-(7bS,11aR)-6,7,8,9,1...)
Affinity DataKi:  106nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2C receptor using [125I]-DOI as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed