BDBM50125248 5-(Acetylamino-methyl)-3-(3-amino-4-chloro-phenyl)-4,5-dihydro-isoxazole-5-carboxylic acid [5-(2-sulfamoyl-phenyl)-pyridin-2-yl]-amide::CHEMBL267681

SMILES CC(=O)NCC1(CC(=NO1)c1ccc(Cl)c(N)c1)C(=O)Nc1ccc(cn1)-c1ccccc1S(N)(=O)=O

InChI Key InChIKey=DZADXUOYDHUVHY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50125248   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125248(5-(Acetylamino-methyl)-3-(3-amino-4-chloro-phenyl)...)
Affinity DataKi:  11nMAssay Description:Inhibitory activity against Rabbit factor Xa was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125248(5-(Acetylamino-methyl)-3-(3-amino-4-chloro-phenyl)...)
Affinity DataKi: >1.60E+3nMAssay Description:Inhibitory activity against trypsin using human purified enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125248(5-(Acetylamino-methyl)-3-(3-amino-4-chloro-phenyl)...)
Affinity DataKi: >2.10E+4nMAssay Description:Inhibitory activity against thrombin using human purified enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed