BDBM50125264 CHEMBL10600::N-(2-Diethylamino-ethyl)-2-[2-(4-fluoro-benzylsulfanyl)-5-methylsulfanyl-4-oxo-4H-pyrimidin-1-yl]-N-(4'-trifluoromethyl-biphenyl-4-ylmethyl)-acetamide

SMILES CCN(CC)CCN(Cc1ccc(cc1)-c1ccc(cc1)C(F)(F)F)C(=O)Cn1cc(SC)c(=O)nc1SCc1ccc(F)cc1

InChI Key InChIKey=ZMQFSABOKCOPMT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50125264   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50125264(CHEMBL10600 | N-(2-Diethylamino-ethyl)-2-[2-(4-flu...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibitory activity against CYP450 3A4 isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50125264(CHEMBL10600 | N-(2-Diethylamino-ethyl)-2-[2-(4-flu...)
Affinity DataIC50:  0.800nMAssay Description:Inhibitory activity against recombinant human Lp-PLA2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50125264(CHEMBL10600 | N-(2-Diethylamino-ethyl)-2-[2-(4-flu...)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibitory activity against Cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed