BDBM50125267 CHEMBL10501::N-(4'-Chloro-biphenyl-4-ylmethyl)-N-(2-diethylamino-ethyl)-2-[2-(4-fluoro-benzylsulfanyl)-4-oxo-5,6,7,8-tetrahydro-4H-quinazolin-1-yl]-acetamide
SMILES CCN(CC)CCN(Cc1ccc(cc1)-c1ccc(Cl)cc1)C(=O)Cn1c(SCc2ccc(F)cc2)nc(=O)c2CCCCc12
InChI Key InChIKey=RVLMCLGUQRGIEP-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50125267
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against CYP450 3A4 isozymeMore data for this Ligand-Target Pair
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:Inhibitory activity against recombinant human Lp-PLA2More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory activity against Cytochrome P450 2D6More data for this Ligand-Target Pair