BDBM50125513 CHEMBL277598::{4-[(2-Methoxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl}-carbamic acid allyl ester

SMILES C=CCOC(=O)N[C@H]1CC[C@](CNC(=O)c2ccccc2OC)(c2ccccc2)CC1

InChI Key InChIKey=JVCNBEKOOOPXNX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50125513   

TargetPotassium voltage-gated channel subfamily A member 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50125513BDBM50125513({4-[(2-Methoxy-benzoylamino)-methyl]-4-phenyl-cycl...)
Affinity DataIC50: 72nMAssay Description:Inhibition of DiTc binding to Kv1.3 channel in human brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50125513BDBM50125513({4-[(2-Methoxy-benzoylamino)-methyl]-4-phenyl-cycl...)
Affinity DataIC50: 90nMAssay Description:Inhibition of [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50125513BDBM50125513({4-[(2-Methoxy-benzoylamino)-methyl]-4-phenyl-cycl...)
Affinity DataIC50: 354nMAssay Description:Inhibition of T-cell proliferation was determined by a human T-cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed