BDBM50125657 (2R,3S)-4-Cyclohexyl-3-{(S)-2-[2-(3,5-difluoro-phenyl)-acetylamino]-4-methyl-pentanoylamino}-2-hydroxy-butyric acid ethyl ester::CHEMBL19645
SMILES CCOC(=O)[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](CC(C)C)NC(=O)Cc1cc(F)cc(F)c1
InChI Key InChIKey=WRAGBOCAZCEZIG-WPFOTENUSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50125657
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 450nMAssay Description:Inhibition of amyloid beta protein production in transfected H4 (neuroglioma) cells expressing APF constructs.More data for this Ligand-Target Pair