BDBM50126635 3-[3-({[(Z)-amino(imino)methyl]amino}oxy)ethoxy]-5-methylphenyl 2-methylsulfonylbenzenesulfonate::3-[3-({[(Z)-amino(imino)methyl]amino}oxy)propoxy]-5-methylphenyl 2-methylsulfonylbenzenesulfonate::CHEMBL37637

SMILES Cc1cc(OCCCONC(N)=N)cc(OS(=O)(=O)c2ccccc2S(C)(=O)=O)c1

InChI Key InChIKey=CFBZFBMYIQZREO-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50126635   

TargetProthrombin(Human)
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126635(3-[3-({[(Z)-amino(imino)methyl]amino}oxy)ethoxy]-5...)
Affinity DataKi:  11.9nMAssay Description:Inhibitory activity of the compound was tested against alpha-human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126635(3-[3-({[(Z)-amino(imino)methyl]amino}oxy)ethoxy]-5...)
Affinity DataKi:  12nMAssay Description:Inhibitory activity of the compound was tested against alpha-human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetChymotrypsinogen B(Human)
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126635(3-[3-({[(Z)-amino(imino)methyl]amino}oxy)ethoxy]-5...)
Affinity DataKi: >2.20E+4nMAssay Description:In vitro inhibitory activity of the compound was tested against serine protease ChymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126635(3-[3-({[(Z)-amino(imino)methyl]amino}oxy)ethoxy]-5...)
Affinity DataKi: >2.20E+4nMAssay Description:In vitro inhibitory activity of the compound was tested against serine protease FXaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlasminogen(Human)
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126635(3-[3-({[(Z)-amino(imino)methyl]amino}oxy)ethoxy]-5...)
Affinity DataKi: >2.20E+4nMAssay Description:In vitro inhibitory activity of the compound was tested against serine protease PlasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeutrophil elastase(Human)
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126635(3-[3-({[(Z)-amino(imino)methyl]amino}oxy)ethoxy]-5...)
Affinity DataKi: >2.20E+4nMAssay Description:In vitro inhibitory activity of the compound was tested against serine protease ElastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126635(3-[3-({[(Z)-amino(imino)methyl]amino}oxy)ethoxy]-5...)
Affinity DataKi: >2.20E+4nMAssay Description:In vitro inhibitory activity of the compound was tested against serine protease TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein phosphatase PP1-alpha catalytic subunit(Human)
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126635(3-[3-({[(Z)-amino(imino)methyl]amino}oxy)ethoxy]-5...)
Affinity DataKi: >6.70E+4nMAssay Description:In vitro inhibitory activity of the compound was tested against serine protease UrokinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed