BDBM50127054 CHEMBL43937::N-{(4S)-4-amino-5-[(pyridin-3-ylmethyl)amino]pentyl}-N'-nitroguanidine

SMILES N[C@@H](CCCNC(=N)N[N+]([O-])=O)CNCc1cccnc1

InChI Key InChIKey=YFRGVCGJTQQYQT-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50127054   Sort by

TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50127054(N-{(4S)-4-amino-5-[(pyridin-3-ylmethyl)amino]penty...)
Affinity DataKi:  550nMAssay Description:Inhibitory activity against Neuronal Nitric Oxide Synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, brain(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50127054(N-{(4S)-4-amino-5-[(pyridin-3-ylmethyl)amino]penty...)
Affinity DataKi:  760nMAssay Description:Inhibitory activity against neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50127054(N-{(4S)-4-amino-5-[(pyridin-3-ylmethyl)amino]penty...)
Affinity DataKi:  5.23E+5nMAssay Description:Inhibitory activity against endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50127054(N-{(4S)-4-amino-5-[(pyridin-3-ylmethyl)amino]penty...)
Affinity DataKi:  1.41E+5nMAssay Description:Inhibitory activity against Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50127054(N-{(4S)-4-amino-5-[(pyridin-3-ylmethyl)amino]penty...)
Affinity DataKi:  3.95E+5nMAssay Description:Inhibitory activity against Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50127054(N-{(4S)-4-amino-5-[(pyridin-3-ylmethyl)amino]penty...)
Affinity DataKi:  1.93E+5nMAssay Description:Inhibitory activity against endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed