BDBM50127314 5-[(5-Cyano-3'-methoxy-biphenyl-2-ylmethoxy)-(3-methyl-3H-imidazol-4-yl)-methyl]-pyridine-2-carbonitrile::CHEMBL432477

SMILES COc1cccc(c1)-c1cc(ccc1COC(c1cncn1C)c1ccc(nc1)C#N)C#N

InChI Key InChIKey=CCEZIQLQUIJUBR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127314   

LigandPNGBDBM50127314(5-[(5-Cyano-3'-methoxy-biphenyl-2-ylmethoxy)-(3-me...)
Affinity DataIC50:  0.880nMAssay Description:Inhibition of transfer of [3H]-FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGeranylgeranyl transferase type-1 subunit beta(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127314(5-[(5-Cyano-3'-methoxy-biphenyl-2-ylmethoxy)-(3-me...)
Affinity DataIC50: >10nMAssay Description:Inhibition of transfer of [3H]-FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine GGTase-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed