BDBM50127319 5-[(2-Benzo[1,3]dioxol-5-yl-4-cyano-benzyloxy)-(3-methyl-3H-imidazol-4-yl)-methyl]-pyridine-2-carbonitrile::CHEMBL288449

SMILES Cn1cncc1C(OCc1ccc(cc1-c1ccc2OCOc2c1)C#N)c1ccc(nc1)C#N

InChI Key InChIKey=RGMYZJYRYHPFBW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127319   

LigandPNGBDBM50127319(5-[(2-Benzo[1,3]dioxol-5-yl-4-cyano-benzyloxy)-(3-...)
Affinity DataIC50: 0.840nMAssay Description:Inhibition of transfer of [3H]FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGeranylgeranyl transferase type-1 subunit beta(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127319(5-[(2-Benzo[1,3]dioxol-5-yl-4-cyano-benzyloxy)-(3-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of transfer of [3H]FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine GGTase-IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed