BDBM50127484 2-[7-(3,5-Dimethoxy-benzylamino)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-4-methyl-pentanoic acid hydroxyamide::CHEMBL54663

SMILES COc1cc(CNc2ccc3c(NCCN([C@H](CC(C)C)C(=O)NO)S3(=O)=O)c2)cc(OC)c1

InChI Key InChIKey=MAPLEBZZVBOXKC-OAQYLSRUSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50127484   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50127484(2-[7-(3,5-Dimethoxy-benzylamino)-1,1-dioxo-1,3,4,5...)
Affinity DataKi:  56nMAssay Description:In vitro inhibitory activity against porcine tumor necrosis factor alpha converting enzyme (pTACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50127484(2-[7-(3,5-Dimethoxy-benzylamino)-1,1-dioxo-1,3,4,5...)
Affinity DataKi:  75nMAssay Description:In vitro inhibitory activity against broad spectrum matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrix metalloproteinase-9(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50127484(2-[7-(3,5-Dimethoxy-benzylamino)-1,1-dioxo-1,3,4,5...)
Affinity DataKi:  347nMAssay Description:In vitro inhibitory activity against broad spectrum matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterstitial collagenase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50127484(2-[7-(3,5-Dimethoxy-benzylamino)-1,1-dioxo-1,3,4,5...)
Affinity DataKi: >4.95E+3nMAssay Description:In vitro inhibitory activity against broad spectrum matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed