BDBM50127944 (S)-3-Benzo[1,3]dioxol-5-yl-3-(2-{6-cyclopropyl-2-oxo-3-[(5,6,7,8-tetrahydro-[1,8]naphthyridin-2-ylmethyl)-amino]-2H-pyrazin-1-yl}-acetylamino)-propionic acid::CHEMBL51391

SMILES OC(=O)C[C@H](NC(=O)Cn1c(cnc(NCc2ccc3CCCNc3n2)c1=O)C1CC1)c1ccc2OCOc2c1

InChI Key InChIKey=JDAGFAQRQYOYIN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127944   

TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50127944((S)-3-Benzo[1,3]dioxol-5-yl-3-(2-{6-cyclopropyl-2-...)
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against human alpha V beta3 receptor using SPAV3 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50127944((S)-3-Benzo[1,3]dioxol-5-yl-3-(2-{6-cyclopropyl-2-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Ability to bind to the Alpha 2 Beta 3 integrin expressed as inhibitory concentration against ADP-stimulated aggregation of human gel-filtered platele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed