BDBM50127945 (S)-3-(2-{5-Chloro-2-oxo-6-phenyl-3-[(5,6,7,8-tetrahydro-[1,8]naphthyridin-2-ylmethyl)-amino]-2H-pyrazin-1-yl}-acetylamino)-3-(3-fluoro-phenyl)-propionic acid::CHEMBL50698

SMILES OC(=O)C[C@H](NC(=O)Cn1c(c(Cl)nc(NCc2ccc3CCCNc3n2)c1=O)-c1ccccc1)c1cccc(F)c1

InChI Key InChIKey=HJLTYUKBSRWJDT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127945   

TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50127945((S)-3-(2-{5-Chloro-2-oxo-6-phenyl-3-[(5,6,7,8-tetr...)
Affinity DataIC50: 112nMAssay Description:Inhibitory activity against human alpha V beta3 receptor using SPAV3 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50127945((S)-3-(2-{5-Chloro-2-oxo-6-phenyl-3-[(5,6,7,8-tetr...)
Affinity DataIC50: 3.00E+3nMAssay Description:Ability to bind to the Alpha 2 Beta 3 integrin expressed as inhibitory concentration against ADP-stimulated aggregation of human gel-filtered platele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed