BDBM50128649 1-(4-methoxybenzyl)-4-(4-(4-chlorophenoxy)phenylsulfonyl)-N-hydroxypiperidine-4-carboxamide::4-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-1-(4-methoxy-benzyl)-piperidine-4-carboxylic acid hydroxyamide::CHEMBL78909

SMILES COc1ccc(CN2CCC(CC2)(C(=O)NO)S(=O)(=O)c2ccc(Oc3ccc(Cl)cc3)cc2)cc1

InChI Key InChIKey=WZTNVCMELDPHHH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50128649   

LigandPNGBDBM50128649(1-(4-methoxybenzyl)-4-(4-(4-chlorophenoxy)phenylsu...)
Affinity DataIC50:  492nMAssay Description:In vitro inhibitory activity against tumor necrosis factor alpha converting enzyme (TACE).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128649(1-(4-methoxybenzyl)-4-(4-(4-chlorophenoxy)phenylsu...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-9.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128649(1-(4-methoxybenzyl)-4-(4-(4-chlorophenoxy)phenylsu...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128649(1-(4-methoxybenzyl)-4-(4-(4-chlorophenoxy)phenylsu...)
Affinity DataIC50:  490nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed