BDBM50128667 1-Benzyl-4-(4-butoxy-benzenesulfonyl)-piperidine-4-carboxylic acid hydroxyamide::1-benzyl-4-(4-butoxyphenylsulfonyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL309492

SMILES CCCCOc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccccc2)CC1)C(=O)NO

InChI Key InChIKey=SRPXVKQVZQEPFT-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50128667   

LigandPNGBDBM50128667(1-Benzyl-4-(4-butoxy-benzenesulfonyl)-piperidine-4...)
Affinity DataIC50:  154nMAssay Description:In vitro inhibitory activity against tumor necrosis factor alpha converting enzyme (TACE).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128667(1-Benzyl-4-(4-butoxy-benzenesulfonyl)-piperidine-4...)
Affinity DataIC50:  2.38E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128667(1-Benzyl-4-(4-butoxy-benzenesulfonyl)-piperidine-4...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-9.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50128667(1-Benzyl-4-(4-butoxy-benzenesulfonyl)-piperidine-4...)
Affinity DataIC50:  277nMAssay Description:Inhibition of TACE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128667(1-Benzyl-4-(4-butoxy-benzenesulfonyl)-piperidine-4...)
Affinity DataIC50:  3nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50128667(1-Benzyl-4-(4-butoxy-benzenesulfonyl)-piperidine-4...)
Affinity DataIC50:  16nMAssay Description:Inhibition of MMP-13 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50128667(1-Benzyl-4-(4-butoxy-benzenesulfonyl)-piperidine-4...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed