BDBM50128679 CHEMBL77784::N-(1-Carbamoyl-pentyl)-2-[2-(4-dimethylaminomethyl-phenyl)-vinyl]-benzamide

SMILES CCCCC(NC(=O)c1ccccc1\C=C\c1ccc(CN(C)C)cc1)C(N)=O

InChI Key InChIKey=PVEWYPRSIGWUAA-FOCLMDBBSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50128679   

TargetCalpain-1 catalytic subunit(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50128679(CHEMBL77784 | N-(1-Carbamoyl-pentyl)-2-[2-(4-dimet...)
Affinity DataKi:  13.3nMAssay Description:Inhibitory activity against human Calpain 1 isolated from erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin B(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50128679(CHEMBL77784 | N-(1-Carbamoyl-pentyl)-2-[2-(4-dimet...)
Affinity DataKi:  27nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50128679(CHEMBL77784 | N-(1-Carbamoyl-pentyl)-2-[2-(4-dimet...)
Affinity DataIC50:  800nMAssay Description:Inhibition of degradation of tyrosine kinase pp60src by Calpain 1 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed