BDBM50128835 CHEMBL3629360

SMILES O=c1ccc2c([C@@H](O)CNCCc3ccc(CCN4CCC(Cn5cnc([C@](O)(c6ccccc6)C6CCCCC6)n5)CC4)cc3)ccc(O)c2[nH]1

InChI Key InChIKey=OLYUOAVKDLVFLJ-UHFFFAOYSA-N

Data  5 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50128835   

TargetMuscarinic acetylcholine receptor M2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128835BDBM50128835(CHEMBL3629360)
Affinity DataKi:  0.140nMAssay Description:Antagonist activity at muscarinic M2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128835BDBM50128835(CHEMBL3629360)
Affinity DataKi:  0.160nMAssay Description:Antagonist activity at muscarinic M1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128835BDBM50128835(CHEMBL3629360)
Affinity DataKi:  0.290nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128835BDBM50128835(CHEMBL3629360)
Affinity DataKi:  0.350nMAssay Description:Antagonist activity at muscarinic M4 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128835BDBM50128835(CHEMBL3629360)
Affinity DataKi:  1.10nMAssay Description:Antagonist activity at muscarinic M5 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Guinea pig)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128835BDBM50128835(CHEMBL3629360)
Affinity DataEC50:  13nMAssay Description:Agonist activity at beta2 adrenoceptor in guinea pig trachea assessed as inhibition of histamine-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128835BDBM50128835(CHEMBL3629360)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human beta2 adrenoceptor expressed in CHO cells assessed as stumulation of intracellular cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed