BDBM50129073 CHEMBL64612::[1-((3S,4S)-2-Oxo-4-phenoxy-azetidin-3-ylcarbamoyl)-cyclohexyl]-carbamic acid benzyl ester

SMILES O=C(NC1(CCCCC1)C(=O)N[C@H]1[C@@H](NC1=O)Oc1ccccc1)OCc1ccccc1

InChI Key InChIKey=AOOLAAKZAJVJMI-CTNGQTDRSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50129073   

TargetCathepsin K(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129073(CHEMBL64612 | [1-((3S,4S)-2-Oxo-4-phenoxy-azetidin...)
Affinity DataKi:  380nMAssay Description:Inhibitory activity of the compound was measured against Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129073(CHEMBL64612 | [1-((3S,4S)-2-Oxo-4-phenoxy-azetidin...)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibitory activity of the compound was measured against Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129073(CHEMBL64612 | [1-((3S,4S)-2-Oxo-4-phenoxy-azetidin...)
Affinity DataKi:  3.30E+4nMAssay Description:Inhibitory activity of the compound was measured against Cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129073(CHEMBL64612 | [1-((3S,4S)-2-Oxo-4-phenoxy-azetidin...)
Affinity DataKi:  1.40E+5nMAssay Description:Inhibitory activity of the compound was measured against Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed