BDBM50129078 2-((2S,3S)-2-Acetoxy-4-oxo-azetidin-3-ylcarbamoyl)-pyrrolidine-1-carboxylic acid benzyl ester::CHEMBL411932

SMILES CC(=O)O[C@@H]1NC(=O)[C@H]1NC(=O)C1CCCN1C(=O)OCc1ccccc1

InChI Key InChIKey=VRSUHJFYRRJBQO-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50129078   

TargetCathepsin K(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129078(2-((2S,3S)-2-Acetoxy-4-oxo-azetidin-3-ylcarbamoyl)...)
Affinity DataKi:  950nMAssay Description:Inhibitory activity was measured against Cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129078(2-((2S,3S)-2-Acetoxy-4-oxo-azetidin-3-ylcarbamoyl)...)
Affinity DataKi:  1.20E+5nMAssay Description:Inhibitory activity was measured against Cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129078(2-((2S,3S)-2-Acetoxy-4-oxo-azetidin-3-ylcarbamoyl)...)
Affinity DataKi: >1.50E+5nMAssay Description:Inhibitory activity was measured against Cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129078(2-((2S,3S)-2-Acetoxy-4-oxo-azetidin-3-ylcarbamoyl)...)
Affinity DataKi: >1.50E+5nMAssay Description:Inhibitory activity was measured against Cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed