BDBM50129086 CHEMBL3629247::US10434085, Compound dihydrohypothemycin

SMILES [H][C@@]12C[C@H](O)[C@H](O)C(=O)CCC[C@H](C)OC(=O)c3c(O)cc(OC)cc3[C@@]1([H])O2

InChI Key InChIKey=FFROTAADEFYDOT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50129086   

TargetMitogen-activated protein kinase kinase kinase 7(Human)
University of North Carolina At Greensboro

Curated by ChEMBL
LigandPNGBDBM50129086(CHEMBL3629247 | US10434085, Compound dihydrohypoth...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2016
Entry Details Article
PubMed
LigandPNGBDBM50129086(CHEMBL3629247 | US10434085, Compound dihydrohypoth...)
Affinity DataIC50: 3.00E+4nMAssay Description:The assay was performed at BSP Biosience Inc. (5Z)-7-oxozeaenol was used as a positive control. Analogue 3 was not tested due to the short-term stabi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent