BDBM50129289 CHEMBL3627970
SMILES COc1cccc(c1)N1CCC[C@H]1C(=O)\N=C(/N)NCc1cc(Cl)c(NC(C)=O)c(Cl)c1
InChI Key InChIKey=XCMIRMNZMAETLZ-IBGZPJMESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50129289
Affinity DataKi: 260nMpH: 5.0Assay Description:Displacement of [3H]BMS-599240 from BACE1 (unknown origin) expressed in HEK293 cells at pH 5 after 1.5 hrs by Microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Affinity DataKi: 630nMpH: 6.4Assay Description:Displacement of [3H]BMS-599240 from BACE1 (unknown origin) expressed in HEK293 cells at pH 6.4 after 1.5 hrs by Microbeta liquid scintillation counti...More data for this Ligand-Target Pair
Affinity DataEC50: 550nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing APP695 Swedish mutant assessed as reduction of amyloid beta (1 to 40) production after overnight incub...More data for this Ligand-Target Pair