BDBM50129294 CHEMBL3628125
SMILES [H][C@@]12CCCN1c1ccc(OC\C=C\CCNCC(=O)Nc3c(Cl)cc(CN\C(N)=N\C2=O)cc3Cl)cc1
InChI Key InChIKey=INHHPEGPWFCJLB-WHLCUDGSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50129294
Affinity DataKi: 20nMpH: 5.0Assay Description:Displacement of [3H]BMS-599240 from BACE1 (unknown origin) expressed in HEK293 cells at pH 5 after 1.5 hrs by Microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Affinity DataKi: 110nMpH: 6.4Assay Description:Displacement of [3H]BMS-599240 from BACE1 (unknown origin) expressed in HEK293 cells at pH 6.4 after 1.5 hrs by Microbeta liquid scintillation counti...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: >1.30E+4nMAssay Description:Inhibition of human ERG by thallium flux assayMore data for this Ligand-Target Pair
Affinity DataEC50: 230nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing APP695 Swedish mutant assessed as reduction of amyloid beta (1 to 40) production after overnight incub...More data for this Ligand-Target Pair