BDBM50130036 CHEMBL3629279

SMILES Cc1c[nH]c2ncnc(-c3ccc(NC(=O)Nc4cncnc4)c(F)c3)c12

InChI Key InChIKey=HEDMPIZYYJEXOE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50130036   

TargetLIM domain kinase 1(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50130036(CHEMBL3629279)
Affinity DataIC50: 55nMAssay Description:Inhibition of LIMK1 (unknown origin) using 1 uM cofilin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50130036(CHEMBL3629279)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of ROCK2 (unknown origin) after 4 hrs using 1 uM STK2 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed