BDBM50130037 CHEMBL3629278

SMILES Cc1c[nH]c2ncnc(-c3ccc(NC(=O)Nc4ccnc(C)c4)c(F)c3)c12

InChI Key InChIKey=AWSGOVJNEZMVLZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50130037   

TargetLIM domain kinase 1(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50130037(CHEMBL3629278)
Affinity DataIC50: 19nMAssay Description:Inhibition of LIMK1 (unknown origin) using 1 uM cofilin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50130037(CHEMBL3629278)
Affinity DataIC50: 2.01E+3nMAssay Description:Inhibition of ROCK2 (unknown origin) after 4 hrs using 1 uM STK2 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed