BDBM50130292 CHEMBL32029::US11427604, Compound (I-44)::US11597738, Example 2::[2-(4-Methoxy-1H-indol-3-yl)-ethyl]-dimethyl-amine

SMILES COc1cccc2[nH]cc(CCN(C)C)c12

InChI Key InChIKey=HFYHBTWTJDAYGW-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50130292   

Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50130292([2-(4-Methoxy-1H-indol-3-yl)-ethyl]-dimethyl-amine...)
Affinity DataKi:  154nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Mindset Pharma

US Patent
LigandPNGBDBM50130292([2-(4-Methoxy-1H-indol-3-yl)-ethyl]-dimethyl-amine...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2023
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Mindset Pharma

US Patent
LigandPNGBDBM50130292([2-(4-Methoxy-1H-indol-3-yl)-ethyl]-dimethyl-amine...)
Affinity DataIC50: 500nMAssay Description:Table 2: i. Prepare the assay buffer following the table below;Reagent ConcentrationTris 50 mMCaCl2  4 mMBSA 0.1% (w/v)Adjust pH to 7.4 followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent