BDBM50130601 26-[(E)-ethylidene]-19-methoxy-24-methyl-4,24-diazaheptacyclo[12.7.3.22,13.01,13.03,11.05,10.016,21]hexacosa-3(11),5(10),6,8,16(21),17,19-heptaen-20-ol::CHEMBL320306

SMILES C/C=C1\C[C@@]23Cc4c([nH]c5ccccc45)[C@@H]1[C@@]21CCN(C)C3Cc2ccc(OC)c(O)c21

InChI Key InChIKey=LCAPOJSUBMKLGT-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50130601   

TargetDelta-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130601BDBM50130601(26-[(E)-ethylidene]-19-methoxy-24-methyl-4,24-diaz...)
Affinity DataKi:  83nMAssay Description:Binding affinity for human Opioid receptor delta 1 transfected into chinese hamster ovary cells by displacing [3H]CI-DPDPE radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130601BDBM50130601(26-[(E)-ethylidene]-19-methoxy-24-methyl-4,24-diaz...)
Affinity DataKi:  122nMAssay Description:Binding affinity for human Opioid receptor mu 1 transfected into chinese hamster ovary cells by displacing [3H]DAMGO radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130601BDBM50130601(26-[(E)-ethylidene]-19-methoxy-24-methyl-4,24-diaz...)
Affinity DataEC50:  221nMAssay Description:Agonistic activity towards Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130601BDBM50130601(26-[(E)-ethylidene]-19-methoxy-24-methyl-4,24-diaz...)
Affinity DataKi:  239nMAssay Description:Binding affinity in recombinant human Opioid receptor kappa 1 transfected into chinese hamster ovary cells by displacing [3H]U-69593 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130601BDBM50130601(26-[(E)-ethylidene]-19-methoxy-24-methyl-4,24-diaz...)
Affinity DataEC50:  1.64E+3nMAssay Description:Effective concentration agonistic activity towards Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130601BDBM50130601(26-[(E)-ethylidene]-19-methoxy-24-methyl-4,24-diaz...)
Affinity DataEC50:  2.21E+3nMAssay Description:Agonistic activity towards opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed