BDBM50130602 3-hydroxy-4-methoxy-17-methyl-18-[1-phenyl-(E)-methylidene]-17-azapentacyclo[7.5.3.210,14.01,10.02,7]nonadeca-2(7),3,5-trien-13-one::CHEMBL109040

SMILES COc1ccc2c(c1O)[C@]13CCN(C)C(C2)[C@]12CCC(=O)[C@H]3/C(=C/c1ccccc1)C2

InChI Key InChIKey=RNXZIQREMYDCBE-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50130602   

TargetKappa-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130602BDBM50130602(3-hydroxy-4-methoxy-17-methyl-18-[1-phenyl-(E)-met...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity in recombinant human Opioid receptor kappa 1 transfected into chinese hamster ovary cells by displacing [3H]U-69593 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130602BDBM50130602(3-hydroxy-4-methoxy-17-methyl-18-[1-phenyl-(E)-met...)
Affinity DataKi:  0.430nMAssay Description:Binding affinity for human Opioid receptor mu 1 transfected into chinese hamster ovary cells by displacing [3H]DAMGO radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130602BDBM50130602(3-hydroxy-4-methoxy-17-methyl-18-[1-phenyl-(E)-met...)
Affinity DataEC50:  4.20nMAssay Description:Agonistic activity towards Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130602BDBM50130602(3-hydroxy-4-methoxy-17-methyl-18-[1-phenyl-(E)-met...)
Affinity DataKi:  5.5nMAssay Description:Binding affinity for human Opioid receptor delta 1 transfected into chinese hamster ovary cells by displacing [3H]CI-DPDPE radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130602BDBM50130602(3-hydroxy-4-methoxy-17-methyl-18-[1-phenyl-(E)-met...)
Affinity DataEC50:  6.70nMAssay Description:Effective concentration agonistic activity towards Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130602BDBM50130602(3-hydroxy-4-methoxy-17-methyl-18-[1-phenyl-(E)-met...)
Affinity DataEC50:  18nMAssay Description:Agonistic activity towards Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed