BDBM50131212 CHEMBL3634531

SMILES Nc1n[nH]c2cccc(-c3ccc(cc3)C(=O)N3CCN(CC3)C(=O)c3cccc(c3)C(F)(F)F)c12

InChI Key InChIKey=ZCYQLRDWLRATNH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50131212   

TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
First Affiliated Hospital of Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50131212(CHEMBL3634531)
Affinity DataIC50: 2.76E+3nMAssay Description:Inhibition of wild type Bcr-Abl (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
First Affiliated Hospital of Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50131212(CHEMBL3634531)
Affinity DataIC50: 9.46E+4nMAssay Description:Inhibition of Bcr-Abl T315I mutant (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed