BDBM50131226 CHEMBL3634770::US9260425, 234

SMILES Cn1cc(cn1)-c1cc2c(n[nH]c2cn1)-c1cccc(n1)N1CCNCC1

InChI Key InChIKey=DDJSMJOXPLNBBR-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50131226   

TargetSerine/threonine-protein kinase pim-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50131226(CHEMBL3634770 | US9260425, 234)
Affinity DataKi:  0.0170nMAssay Description:Inhibition of Pim3 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase pim-1(Human)
Genetech

US Patent
LigandPNGBDBM50131226(CHEMBL3634770 | US9260425, 234)
Affinity DataKi:  0.0360nMpH: 7.2Assay Description:PIM-1, PIM-2, and PIM-3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J....More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetSerine/threonine-protein kinase pim-1(Human)
Genetech

US Patent
LigandPNGBDBM50131226(CHEMBL3634770 | US9260425, 234)
Affinity DataKi:  0.0360nMAssay Description:Inhibition of Pim1 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase pim-2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50131226(CHEMBL3634770 | US9260425, 234)
Affinity DataKi:  0.580nMAssay Description:Inhibition of Pim2 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed