BDBM50131468 (S)-24-Chloro-11-(R)-cyclohexyl-20-oxa-3,9,12,17-tetraaza-tricyclo[19.4.0.0*5,9*]pentacosa-1(21),22,24-triene-4,10,13,18-tetraone::CHEMBL93315

SMILES Clc1ccc2OCC(=O)NCCCC(=O)N[C@H](C3CCCCC3)C(=O)N3CCC[C@H]3C(=O)NCc2c1

InChI Key InChIKey=ZKEXKWQUJJJULZ-GBXCKJPGSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50131468   

TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50131468((S)-24-Chloro-11-(R)-cyclohexyl-20-oxa-3,9,12,17-t...)
Affinity DataKi:  0.400nMAssay Description:Inhibitory activity against thrombin IIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50131468((S)-24-Chloro-11-(R)-cyclohexyl-20-oxa-3,9,12,17-t...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50131468((S)-24-Chloro-11-(R)-cyclohexyl-20-oxa-3,9,12,17-t...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50131468((S)-24-Chloro-11-(R)-cyclohexyl-20-oxa-3,9,12,17-t...)
Affinity DataKi:  8.90E+3nMAssay Description:Inhibitory activity against Tissue plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed