BDBM50131564 2-[4-(2,4-Diamino-quinazolin-6-ylmethoxycarbonyl)-benzoylamino]-hexanedioic acid::CHEMBL419946

SMILES Nc1nc(N)c2cc(COC(=O)c3ccc(cc3)C(=O)N[C@@H](CCCC(O)=O)C(O)=O)ccc2n1

InChI Key InChIKey=GJUWHLSSVGPWOZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50131564   

TargetDihydrofolate reductase(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50131564(2-[4-(2,4-Diamino-quinazolin-6-ylmethoxycarbonyl)-...)
Affinity DataIC50: 160nMAssay Description:Inhibition of rat liver Dihydrofolate reductase (rlDHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed