BDBM50132080 Biphenyl-4-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide; oxalic acid::CHEMBL112065::CHEMBL129483
SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(cc2)-c2ccccc2)CC1
InChI Key InChIKey=OJZXUFDBDMQATJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50132080
Affinity DataKi: 0.220nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]spiroperidol from cloned human dopamine receptor D3 in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]spiperone from wild type human dopamine D3 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 2.85nMAssay Description:Binding affinity for human dopamine receptor D3 by displacing [125I]-iodosulpiride expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:Displacement of [3H]spiperone from human dopamine D2short receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:Displacement of [3H]spiperone from human dopamine D2long receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 75nMAssay Description:Binding affinity for human dopamine receptor D2 by displacing [125I]-iodosulpiride expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 570nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor in porcine cerebral cortex after 60 minsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Biocon-Bristol Myers Squibb Research and Development Centre
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Centre
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of hERG channelMore data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Partial agonist activity at human dopamine D2long receptor expressed in CHO cells assessed as induction of [3H]thymidine incorporation after 2 hrsMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Human)
Biocon-Bristol Myers Squibb Research and Development Centre
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Centre
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair