BDBM50132372 2-(4-tert-Butyl-phenyl)-6-morpholin-4-yl-thiopyran-4-one::6-(4-t-butylphenyl)-2-morpholin-4-yl-4H-thiopyran-4-one::CHEMBL102396

SMILES CC(C)(C)c1ccc(cc1)-c1cc(=O)cc(s1)N1CCOCC1

InChI Key InChIKey=MROJZDSJVHDFKF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132372   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50132372(2-(4-tert-Butyl-phenyl)-6-morpholin-4-yl-thiopyran...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of DNA-PK in HeLa cell nuclear extractsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDNA-dependent protein kinase catalytic subunit(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50132372(2-(4-tert-Butyl-phenyl)-6-morpholin-4-yl-thiopyran...)
Affinity DataIC50:  920nMAssay Description:In vitro inhibition of DNA-dependent protein kinase(DNA-PK) from HeLa (human carcinoma) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed