BDBM50132474 CHEMBL3634611::US9751873, Example 32

SMILES C[C@H]1CC[C@H](c2ccccc2)S(=O)(=O)N1Cc1ccc(cc1F)C1(CCN(CC1)C(C)=O)OC(N)=O

InChI Key InChIKey=XPUAHLBEVYGVFF-MHECFPHRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132474   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50132474(CHEMBL3634611 | US9751873, Example 32)
Affinity DataIC50:  410nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50132474(CHEMBL3634611 | US9751873, Example 32)
Affinity DataIC50:  410nMAssay Description:Inhibition of [3H]-FPP incorporation into biotin-linked K-ras decapeptide (CVIM) by bovine farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed