BDBM50132898 CHEMBL115142::Dibutyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyrazolo[4,3-b]pyridin-7-yl]-amine
SMILES CCCCN(CCCC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl
InChI Key InChIKey=VLHIKSVDLITNMK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50132898
Affinity DataKi: 0.620nMAssay Description:Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.620nMAssay Description:Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of Corticotropin releasing factor receptor 1-stimulated cAMP productionMore data for this Ligand-Target Pair