BDBM50133120 5-{3-[3,5-Diisopropyl-2-(2,2,2-trifluoro-ethoxy)-phenyl]-thiophen-2-yl}-3-methyl-penta-2,4-dienoic acid::CHEMBL132488

SMILES CC(C)c1cc(C(C)C)c(OCC(F)(F)F)c(c1)-c1ccsc1\C=C\C(\C)=C\C(O)=O

InChI Key InChIKey=XMMBYJXSOLEASQ-XDHFRCMDSA-N

Data  8 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50133120   

TargetRetinoic acid receptor RXR-alpha(Rat)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50133120(5-{3-[3,5-Diisopropyl-2-(2,2,2-trifluoro-ethoxy)-p...)
Affinity DataKi:  8.70nMAssay Description:Binding affinity for Retinoic acid receptor RXR-alpha was determined by competing with 3[H]-9-cis-RAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRetinoic acid receptor RXR-beta(Rat)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50133120(5-{3-[3,5-Diisopropyl-2-(2,2,2-trifluoro-ethoxy)-p...)
Affinity DataKi:  15nMAssay Description:Binding affinity for Retinoic acid receptor RXR-beta was determined by competing with 3[H]-9-cis-RAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRetinoic acid receptor RXR-gamma(Rat)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50133120(5-{3-[3,5-Diisopropyl-2-(2,2,2-trifluoro-ethoxy)-p...)
Affinity DataKi:  18nMAssay Description:Binding affinity for Retinoic acid receptor RXR-gamma was determined by competing with 3[H]-9-cis-RAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRetinoic acid receptor, alpha, isoform CRA_b(Rat)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50133120(5-{3-[3,5-Diisopropyl-2-(2,2,2-trifluoro-ethoxy)-p...)
Affinity DataKi:  3.44E+3nMAssay Description:Binding affinity for Retinoic acid receptor alpha was determined by competing with 3[H]-ATRAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPeroxisome proliferator-activated receptor gamma(Rat)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50133120(5-{3-[3,5-Diisopropyl-2-(2,2,2-trifluoro-ethoxy)-p...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for Peroxisome proliferator activated receptor gamma was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPeroxisome proliferator-activated receptor alpha(Rat)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50133120(5-{3-[3,5-Diisopropyl-2-(2,2,2-trifluoro-ethoxy)-p...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for peroxisome Peroxisome proliferator activated receptor alpha was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRetinoic acid receptor, gamma(Rat)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50133120(5-{3-[3,5-Diisopropyl-2-(2,2,2-trifluoro-ethoxy)-p...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for Retinoic acid receptor gamma was determined by competing with 3[H]-ATRAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRetinoic acid receptor beta(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50133120(5-{3-[3,5-Diisopropyl-2-(2,2,2-trifluoro-ethoxy)-p...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for Retinoic acid receptor beta was determined by competing with 3[H]-ATRAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRetinoic acid receptor RXR-alpha(Rat)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50133120(5-{3-[3,5-Diisopropyl-2-(2,2,2-trifluoro-ethoxy)-p...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibition of 5-(125I)A-85380 binding to nicotinic acetylcholine receptor (nAChR) of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed