BDBM50133148 5-[1-(2-Bromo-phenyl)-meth-(Z)-ylidene]-9-fluoro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::CHEMBL334586

SMILES CC1=CC(C)(C)Nc2ccc3-c4cc(F)ccc4O\C(=C/c4ccccc4Br)c3c12

InChI Key InChIKey=PLBNJBDMVLYMMO-FMCGGJTJSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50133148   

TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50133148(5-[1-(2-Bromo-phenyl)-meth-(Z)-ylidene]-9-fluoro-2...)
Affinity DataKi:  16.4nMAssay Description:Binding affinity towards human progesterone receptor A isoform using progesterone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50133148(5-[1-(2-Bromo-phenyl)-meth-(Z)-ylidene]-9-fluoro-2...)
Affinity DataEC50:  9nMAssay Description:Agonistic activity against human progesterone receptor in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50133148(5-[1-(2-Bromo-phenyl)-meth-(Z)-ylidene]-9-fluoro-2...)
Affinity DataEC50:  50nMAssay Description:Agonistic activity against human progesterone receptor in T47D breast cancer cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed