BDBM50133363 CHEMBL541455::N-(2-(furan-2-yl)-8-phenethyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-2-phenylacetamide::N-(2-Furan-2-yl-8-phenethyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-2-phenyl-acetamide

SMILES O=C(Cc1ccccc1)Nc1nc2nn(CCc3ccccc3)cc2c2nc(nn12)-c1ccco1

InChI Key InChIKey=NNKNPNUOGFMYAG-UHFFFAOYSA-N

Data  8 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50133363   

TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50133363(CHEMBL541455 | N-(2-(furan-2-yl)-8-phenethyl-8H-py...)
Affinity DataKi:  5.49nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50133363(CHEMBL541455 | N-(2-(furan-2-yl)-8-phenethyl-8H-py...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A2B receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50133363(CHEMBL541455 | N-(2-(furan-2-yl)-8-phenethyl-8H-py...)
Affinity DataKi:  43.9nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50133363(CHEMBL541455 | N-(2-(furan-2-yl)-8-phenethyl-8H-py...)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]-MRE3008-F20 from human A3 receptors expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50133363(CHEMBL541455 | N-(2-(furan-2-yl)-8-phenethyl-8H-py...)
Affinity DataKi:  45nMAssay Description:Antagonist activity at human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50133363(CHEMBL541455 | N-(2-(furan-2-yl)-8-phenethyl-8H-py...)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]-ZM-241,385 from human adenosine A2A receptors expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50133363(CHEMBL541455 | N-(2-(furan-2-yl)-8-phenethyl-8H-py...)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]-DPCPX from human Adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50133363(CHEMBL541455 | N-(2-(furan-2-yl)-8-phenethyl-8H-py...)
Affinity DataKi:  128nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50133363(CHEMBL541455 | N-(2-(furan-2-yl)-8-phenethyl-8H-py...)
Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-induced adenylyl cyclase activityChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50133363(CHEMBL541455 | N-(2-(furan-2-yl)-8-phenethyl-8H-py...)
Affinity DataIC50:  210nMAssay Description:Inhibitory activity against NECA stimulated cAMP accumulation in CHO cells expressing human adenosine A2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed