BDBM50133900 CHEMBL1258798

SMILES Cn1cncc1CN(CCN(Cc1ccccc1)S(=O)(=O)C1CC1)c1ccc(cc1)C#N

InChI Key InChIKey=XFFWOIGDSJUTPZ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50133900   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Yale University

Curated by ChEMBL

LigandBDBM50133900(CHEMBL1258798)Copy SMILESCopy InChI

Affinity DataIC50: 85nMAssay Description:Inhibition of human farnesyltransferase assessed as incorporation of [3H]FPP into H-Ras-CVLSMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/12/2011
Entry Details Article
Copy BDB DOIPubMed
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TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Yale University

Curated by ChEMBL

LigandBDBM50133900(CHEMBL1258798)Copy SMILESCopy InChI

Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of human geranylgeranyltransferase-1 assessed as incorporation of [3H]GGPP into H-Ras-CVLLMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/12/2011
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL