BDBM50133911 CHEMBL508413

SMILES Cn1cnc(c1)S(=O)(=O)N(Cc1ccccc1)[C@@H]1CC[C@H](C1)N(Cc1cncn1C)c1ccc(cc1)C#N

InChI Key InChIKey=SATRSUYMLHSAMT-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50133911   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Yale University

Curated by ChEMBL

LigandBDBM50133911(CHEMBL508413)Copy SMILESCopy InChI

Affinity DataIC50: 380nMAssay Description:Inhibition of human farnesyltransferase assessed as incorporation of [3H]FPP into H-Ras-CVLSMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/12/2011
Entry Details Article
Copy BDB DOIPubMed
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TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Yale University

Curated by ChEMBL

LigandBDBM50133911(CHEMBL508413)Copy SMILESCopy InChI

Affinity DataIC50: 7.05E+3nMAssay Description:Inhibition of human geranylgeranyltransferase-1 assessed as incorporation of [3H]GGPP into H-Ras-CVLLMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/12/2011
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL