BDBM50134039 CHEMBL1256441

SMILES Cn1cnc(c1)S(=O)(=O)N(CCN(Cc1cncn1C)c1c(F)c(F)c(C#N)c(F)c1F)CC1CCN(CC1)c1ncccn1

InChI Key InChIKey=CZZDIMRZFKCVOS-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134039   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Yale University

Curated by ChEMBL

LigandBDBM50134039(CHEMBL1256441)Copy SMILESCopy InChI

Affinity DataIC50: 490nMAssay Description:Inhibition of human farnesyltransferase assessed as incorporation of [3H]FPP into H-Ras-CVLSMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/12/2011
Entry Details Article
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TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Yale University

Curated by ChEMBL

LigandBDBM50134039(CHEMBL1256441)Copy SMILESCopy InChI

Affinity DataIC50: 8.75E+3nMAssay Description:Inhibition of human geranylgeranyltransferase-1 assessed as incorporation of [3H]GGPP into H-Ras-CVLLMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/12/2011
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL