BDBM50134306 CHEMBL3747446

SMILES CN1CCN(CC1)c1nc(Nc2ccc(F)cc2)nc(Nc2ccc3n(Cc4ccccc4)c(C)nc3c2)n1

InChI Key InChIKey=ZPJGCXRVXZJXCO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134306   

TargetDihydrofolate reductase(Human)
Thapar University

Curated by ChEMBL
LigandPNGBDBM50134306(CHEMBL3747446)
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant DHFR expressed in Escherichia coli by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed