BDBM50134386 CHEMBL3747655

SMILES COc1cccc(Nc2c(cnc3c(C)cnn23)C(N)=O)c1

InChI Key InChIKey=UVIPZDMLXGFTOC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50134386   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134386(CHEMBL3747655)
Affinity DataIC50: 165nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134386(CHEMBL3747655)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134386(CHEMBL3747655)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PDE3 by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed