BDBM50134587 CHEMBL3746157

SMILES NC(=O)c1nc(-c2ccns2)c2ccccn12

InChI Key InChIKey=YTNDIPNEFMPJKF-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134587   

TargetMitogen-activated protein kinase 14(Human)
Takeda California

Curated by ChEMBL

LigandBDBM50134587(CHEMBL3746157)Copy SMILESCopy InChI

Affinity DataIC50:  370nMAssay Description:Inhibition of p38alpha phosphorylation in human TNFalpha-stimulated U937 cells treated 1 hr before by ELISAMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
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TargetDual specificity mitogen-activated protein kinase kinase 3(Human)
Takeda California

Curated by ChEMBL

LigandBDBM50134587(CHEMBL3746157)Copy SMILESCopy InChI

Affinity DataIC50:  4nMAssay Description:Inhibition of MKK3 (unknown origin) using [gamma-33P]-ATP after 20 mins by radiometric assayMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL