BDBM50135109 CHEMBL3746067
SMILES COc1ccc(cc1)-c1nc2c(NCC3CCNCC3)c(Cl)cnc2[nH]1
InChI Key InChIKey=YNNNBSQQVGIBKM-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50135109
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of N-terminal GST-fused recombinant JAK2 (831 to 1132 residues) (unknown origin) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of N-terminal GST-fused recombinant JAK3 (781 to 1124 residues) (unknown origin) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 a...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of N-terminal GST-fused human recombinant JAK1 (866 to 1154 residues) expressed in insect cells using FITC-C6-KKHTDDGYMPMSPGVA-NH2 as subs...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of JAK1 in human NCI-H1975 cells assessed as reduction in STAT3 phosphorylation after 2 hrsMore data for this Ligand-Target Pair